Expression Pattern, Regulation, and Biological Role of Runt Domain Transcription Factor, run , in Caenorhabditis elegans
نویسندگان
چکیده
منابع مشابه
Regulation of transcription termination in the nematode Caenorhabditis elegans
The current predicted mechanisms that describe RNA polymerase II (pol II) transcription termination downstream of protein expressing genes fail to adequately explain, how premature termination is prevented in eukaryotes that possess operon-like structures. Here we address this issue by analysing transcription termination at the end of single protein expressing genes and genes located within ope...
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Caenorhabditis elegans is a powerful model for studying gene regulation, as it has a compact genome and a wealth of genomic tools. However, identification of regulatory elements has been limited, as DNA-binding motifs are known for only 71 of the estimated 763 sequence-specific transcription factors (TFs). To address this problem, we performed protein binding microarray experiments on represent...
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Objective: Oxidative stress that damages proteins result in aging and age related diseases. The aim of this study is to determine the effect of tocotrienol rich fraction (TRF) on the expression of proteins in oxidative stress-induced caenohabditis elegans (C.elegans) which has homologous genes to humans. Methods: The worms were treated with TRF prior to, after and continuously in separate group...
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Initially it was believed that when ELT-2 was knocked out in nematodes this caused the nematodes to become sick from all pathogens, even ones that were not previously pathogenic. However, an experiment conducted later suggested that in older cultures of bacteria the ELT-2 knocked out nematodes do not become sick from pathogens that were previously nonpathogenic. In order to clarify the role of ...
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ژورنال
عنوان ژورنال: Molecular and Cellular Biology
سال: 2002
ISSN: 0270-7306,1098-5549
DOI: 10.1128/mcb.22.2.547-554.2002